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Single stranded DNA translocation of E. coli UvrD monomer is tightly coupled to ATP hydrolysis
E. coli UvrD is an SF1A helicase/translocase that functions in several DNA repair pathways. A UvrD monomer is a rapid and processive single-stranded (ss) DNA translocase, but is unable to unwind DNA processively in vitro. Based on data at saturating ATP (500 μM) we proposed a non-uniform stepping me...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3311787/ https://ncbi.nlm.nih.gov/pubmed/22342931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.02.013 |
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