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Systemic κ-Opioid Receptor Antagonism by Nor-binaltorphimine Reduces Dependence-Induced Excessive Alcohol Self-Administration in Rats

Altered dynorphin opioid peptide systems contribute to increased ethanol self-administration during withdrawal following chronic alcohol exposure. We previously identified that the κ-opioid receptor antagonist, nor-binaltorphimine (nor-BNI), selectively reduced ethanol self-administration in depende...

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Detalhes bibliográficos
Main Authors: Walker, Brendan M., Zorrilla, Eric P., Koob, George F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988980/
https://ncbi.nlm.nih.gov/pubmed/20579007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1369-1600.2010.00226.x
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