Ultra-long antagonism of kappa opioid agonist-induced diuresis by intracisternal nor-binaltorphimine in monkeys

Kappa opioid receptor (KOR) agonists such as U-50488H and bremazocine are analgesics and diuretics. In monkeys, the selective KOR antagonist, nor-binaltorphimine (nor-BNI), produces a long-lasting antagonism of the antinociceptive effects of U-50488H but not those of bremazocine, suggesting that KOR...

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Main Authors: Ko, M.C.H., Willmont, K.J., Lee, H., Flory, G.S., Woods, J.H.
格式: Artigo
語言:Inglês
出版: 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863110/
https://ncbi.nlm.nih.gov/pubmed/12915238
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