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The α(1) Adrenergic Receptor Antagonist Prazosin Reduces Heroin Self-Administration in Rats with Extended Access to Heroin Administration

Previous studies have reported that noradrenergic antagonists alleviate some of the symptoms of opiate withdrawal and dependence. Clinical studies also have shown that modification of the noradrenergic system may help protect patients from relapse. The present study tested the hypothesis that a dysr...

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Autores principales: Greenwell, Thomas N., Walker, Brendan M., Cottone, Pietro, Zorrilla, Eric P., Koob, George F.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637926/
https://ncbi.nlm.nih.gov/pubmed/18703080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2008.07.012
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