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The α(1) Adrenergic Receptor Antagonist Prazosin Reduces Heroin Self-Administration in Rats with Extended Access to Heroin Administration

Previous studies have reported that noradrenergic antagonists alleviate some of the symptoms of opiate withdrawal and dependence. Clinical studies also have shown that modification of the noradrenergic system may help protect patients from relapse. The present study tested the hypothesis that a dysr...

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Detalhes bibliográficos
Main Authors: Greenwell, Thomas N., Walker, Brendan M., Cottone, Pietro, Zorrilla, Eric P., Koob, George F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637926/
https://ncbi.nlm.nih.gov/pubmed/18703080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2008.07.012
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