Identification of Key Functional Residues in the Active Site of Human β1,4-Galactosyltransferase 7: A MAJOR ENZYME IN THE GLYCOSAMINOGLYCAN SYNTHESIS PATHWAY

Glycosaminoglycans (GAGs) play a central role in many pathophysiological events, and exogenous xyloside substrates of β1,4-galactosyltransferase 7 (β4GalT7), a major enzyme of GAG biosynthesis, have interesting biomedical applications. To predict functional peptide regions important for substrate bi...

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Autors principals: Talhaoui, Ibtissam, Bui, Catherine, Oriol, Rafael, Mulliert, Guillermo, Gulberti, Sandrine, Netter, Patrick, Coughtrie, Michael W. H., Ouzzine, Mohamed, Fournel-Gigleux, Sylvie
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
Matèries:
Enzymology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988340/
https://ncbi.nlm.nih.gov/pubmed/20843813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.151951
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