Hepatic Overexpression of a Constitutively Active Form of Liver Glycogen Synthase Improves Glucose Homeostasis

In this study, we tested the efficacy of increasing liver glycogen synthase to improve blood glucose homeostasis. The overexpression of wild-type liver glycogen synthase in rats had no effect on blood glucose homeostasis in either the fed or the fasted state. In contrast, the expression of a constit...

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Bibliografiske detaljer
Main Authors: Ros, Susana, Zafra, Delia, Valles-Ortega, Jordi, García-Rocha, Mar, Forrow, Stephen, Domínguez, Jorge, Calbó, Joaquim, Guinovart, Joan J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Metabolism
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988323/
https://ncbi.nlm.nih.gov/pubmed/20841354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.157396
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