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Tungstate Reduces the Expression of Gluconeogenic Enzymes in STZ Rats

AIMS: Oral administration of sodium tungstate has shown hyperglycemia-reducing activity in several animal models of diabetes. We present new insights into the mechanism of action of tungstate. METHODS: We studied protein expression and phosphorylation in the liver of STZ rats, a type I diabetes mode...

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Detalhes bibliográficos
Main Authors: Nocito, Laura, Zafra, Delia, Calbó, Joaquim, Domínguez, Jorge, Guinovart, Joan J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414523/
https://ncbi.nlm.nih.gov/pubmed/22905122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042305
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