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A discrete structure of an RNA folding intermediate revealed by cryo-electron microscopy

RNA folding occurs via a series of transitions between metastable intermediate states. It is unknown whether folding intermediates are discrete structures folding along defined pathways or heterogeneous ensembles folding along broad landscapes. We use cryo-electron microscopy and single particle ima...

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Hlavní autoři: Baird, Nathan J., Ludtke, Steven J., Khant, Htet, Chiu, Wah, Pan, Tao, Sosnick, Tobin R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988076/
https://ncbi.nlm.nih.gov/pubmed/21038867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja107492b
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