Structural Mechanism of SDS-induced Enzyme Activity of Scorpion Hemocyanin Revealed by Electron Cryo-Microscopy

Phenoloxidases (POs) occur in all organisms and are involved in skin and hair coloring in mammals, and initiating melanisation in wound healing. Mutation or overexpression of PO can cause albinism or melanoma, respectively. SDS can convert inactive PO and the oxygen carrier hemocyanin (Hc) into enzy...

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Detalhes bibliográficos
Main Authors: Cong, Yao, Zhang, Qinfen, Woolford, David, Schweikardt, Thorsten, Khant, Htet, Dougherty, Matthew, Ludtke, Steven J, Chiu, Wah, Decker, Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705691/
https://ncbi.nlm.nih.gov/pubmed/19446530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.03.005
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