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A discrete structure of an RNA folding intermediate revealed by cryo-electron microscopy
RNA folding occurs via a series of transitions between metastable intermediate states. It is unknown whether folding intermediates are discrete structures folding along defined pathways or heterogeneous ensembles folding along broad landscapes. We use cryo-electron microscopy and single particle ima...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2988076/ https://ncbi.nlm.nih.gov/pubmed/21038867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja107492b |
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