Evidence for both copy number and allelic (NA1/NA2) risk at the FCGR3B locus in systemic lupus erythematosus

The Fcγ-receptor locus on chromosome 1q23 shows copy-number variation (CNV), and it has previously been shown that individuals with reduced numbers of copies of the Fcγ-receptor-IIIB gene (FCGR3B) have an increased risk of developing systemic lupus erythematosus (SLE). It is not understood whether t...

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Autori principali: Morris, David L, Roberts, Amy L, Witherden, Abigail S, Tarzi, Ruth, Barros, Paula, Whittaker, John C, Cook, Terence H, Aitman, Timothy J, Vyse, Timothy J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987408/
https://ncbi.nlm.nih.gov/pubmed/20442749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2010.56
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