Genomic Pathology of SLE-Associated Copy-Number Variation at the FCGR2C/FCGR3B/FCGR2B Locus

Reduced FCGR3B copy number is associated with increased risk of systemic lupus erythematosus (SLE). The five FCGR2/FCGR3 genes are arranged across two highly paralogous genomic segments on chromosome 1q23. Previous studies have suggested mechanisms for structural rearrangements at the FCGR2/FCGR3 lo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mueller, Michael, Barros, Paula, Witherden, Abigail S., Roberts, Amy L., Zhang, Zhou, Schaschl, Helmut, Yu, Chack-Yung, Hurles, Matthew E., Schaffner, Catherine, Floto, R. Andres, Game, Laurence, Steinberg, Karyn Meltz, Wilson, Richard K., Graves, Tina A., Eichler, Evan E., Cook, H. Terence, Vyse, Timothy J., Aitman, Timothy J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542466/
https://ncbi.nlm.nih.gov/pubmed/23261299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2012.11.013
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