A genome-wide linkage scan reveals CD53 as an important regulator of innate TNF-α levels

Cytokines are major immune system regulators. Previously, innate cytokine profiles determined by lipopolysaccharide stimulation were shown to be highly heritable. To identify regulating genes in innate immunity, we analyzed data from a genome-wide linkage scan using microsatellites in osteoarthritis...

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Detalhes bibliográficos
Main Authors: Bos, Steffan D, Lakenberg, Nico, van der Breggen, Ruud, Houwing-Duistermaat, Jeanine J, Kloppenburg, Margreet, de Craen, Anton JM, Beekman, Marian, Meulenbelt, Ingrid, Slagboom, P Eline
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987381/
https://ncbi.nlm.nih.gov/pubmed/20407468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2010.52
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