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A genome-wide linkage scan reveals CD53 as an important regulator of innate TNF-α levels

Cytokines are major immune system regulators. Previously, innate cytokine profiles determined by lipopolysaccharide stimulation were shown to be highly heritable. To identify regulating genes in innate immunity, we analyzed data from a genome-wide linkage scan using microsatellites in osteoarthritis...

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Main Authors: Bos, Steffan D, Lakenberg, Nico, van der Breggen, Ruud, Houwing-Duistermaat, Jeanine J, Kloppenburg, Margreet, de Craen, Anton JM, Beekman, Marian, Meulenbelt, Ingrid, Slagboom, P Eline
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987381/
https://ncbi.nlm.nih.gov/pubmed/20407468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2010.52
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