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Gemcitabine causes minimal modulation of carboplatin-DNA monoadduct formation and repair in bladder cancer cells
We are developing a method to identify cellular resistance to carboplatin by using accelerator mass spectrometry to measure carboplatin-DNA adducts formed from drug microdoses (~1/100(th) the therapeutic dose). Such an approach would be particularly useful if it is still valid in combination chemoth...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2987236/ https://ncbi.nlm.nih.gov/pubmed/21028869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx1003547 |
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