Gemcitabine causes minimal modulation of carboplatin-DNA monoadduct formation and repair in bladder cancer cells

We are developing a method to identify cellular resistance to carboplatin by using accelerator mass spectrometry to measure carboplatin-DNA adducts formed from drug microdoses (~1/100(th) the therapeutic dose). Such an approach would be particularly useful if it is still valid in combination chemoth...

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Detaylı Bibliyografya
Asıl Yazarlar: Wang, Sisi, Zhang, Hongyong, Malfatti, Michael, de Vere White, Ralph, Lara, Primo N., Turteltaub, Kenneth, Henderson, Paul, Pan, Chong-xian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987236/
https://ncbi.nlm.nih.gov/pubmed/21028869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx1003547
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