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Correlation of Platinum Cytotoxicity to Drug-DNA Adduct Levels in a Breast Cancer Cell Line Panel

Platinum drugs, including carboplatin and oxaliplatin, are commonly used chemotherapy drugs that kill cancer cells by forming toxic drug-DNA adducts. These drugs have a proven, but modest, efficacy against several aggressive subtypes of breast cancer but also cause several side effects that can lead...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Chem Res Toxicol
Main Authors: Wang, Sisi, Scharadin, Tiffany M., Zimmermann, Maike, Malfatti, Michael A., Turteltaub, Kenneth W., de Vere White, Ralph, Pan, Chong-Xian, Henderson, Paul T.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538392/
https://ncbi.nlm.nih.gov/pubmed/30381944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.8b00170
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