The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S(12)

Gene targeting studies have shown that the transcription factor SCL is critically important for embryonic hematopoiesis, but the early lethality of SCL null mice has precluded the genetic analysis of its function in the adult. We have now generated a conditional knockout of SCL by using Cre/Lox tech...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Hall, Mark A., Curtis, David J., Metcalf, Donald, Elefanty, Andrew G., Sourris, K., Robb, Lorraine, Göthert, Joachim R., Jane, Stephen M., Begley, C. Glenn
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2003
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298714/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12552125/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0237324100
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk