The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S(12)

Gene targeting studies have shown that the transcription factor SCL is critically important for embryonic hematopoiesis, but the early lethality of SCL null mice has precluded the genetic analysis of its function in the adult. We have now generated a conditional knockout of SCL by using Cre/Lox tech...

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Detaylı Bibliyografya
Asıl Yazarlar: Hall, Mark A., Curtis, David J., Metcalf, Donald, Elefanty, Andrew G., Sourris, K., Robb, Lorraine, Göthert, Joachim R., Jane, Stephen M., Begley, C. Glenn
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 2003
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC298714/
https://ncbi.nlm.nih.gov/pubmed/12552125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0237324100
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