The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S(12)

Gene targeting studies have shown that the transcription factor SCL is critically important for embryonic hematopoiesis, but the early lethality of SCL null mice has precluded the genetic analysis of its function in the adult. We have now generated a conditional knockout of SCL by using Cre/Lox tech...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Hall, Mark A., Curtis, David J., Metcalf, Donald, Elefanty, Andrew G., Sourris, K., Robb, Lorraine, Göthert, Joachim R., Jane, Stephen M., Begley, C. Glenn
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 2003
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298714/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12552125/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0237324100
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