The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S(12)

Gene targeting studies have shown that the transcription factor SCL is critically important for embryonic hematopoiesis, but the early lethality of SCL null mice has precluded the genetic analysis of its function in the adult. We have now generated a conditional knockout of SCL by using Cre/Lox tech...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Hall, Mark A., Curtis, David J., Metcalf, Donald, Elefanty, Andrew G., Sourris, K., Robb, Lorraine, Göthert, Joachim R., Jane, Stephen M., Begley, C. Glenn
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 2003
Onderwerpen:	Biological Sciences
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298714/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12552125/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0237324100
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