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Observation of liquid–liquid phase separation for eye lens γS-crystallin

γS-crystallin (γS) is an important human and bovine eye lens protein involved in maintaining the transparency of the eye. By adding small amounts of polyethylene glycol (PEG) to the binary aqueous bovine γS solutions, we have observed liquid–liquid phase separation (LLPS) at −8°C and revealed that,...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Annunziata, Onofrio, Ogun, Olutayo, Benedek, George B.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Physical Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298710/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12529503/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.242746499
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