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Determination of the energetics governing the regulatory step in growth hormone-induced receptor homodimerization
Signaling in the human growth hormone (hGH)–human GH receptor system is initiated by a controlled sequential two-step hormone-induced dimerization of two hGH receptors via their extracellular domains (ECDs). Little is currently known about the energetics governing the important regulatory step in re...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC298707/ https://ncbi.nlm.nih.gov/pubmed/12552121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0235023100 |
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