Lipopeptide antagonists of growth hormone-releasing hormone with improved antitumor activities

Antagonists of growth hormone-releasing hormone (GHRH) synthesized previously inhibit proliferation of various human cancers, but derivatisation with fatty acids could enhance their clinical efficacy. We synthesized a series of antagonists of GHRH(1-29)NH(2) acylated at the N terminus with monocarbo...

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Bibliografiska uppgifter
Huvudupphovsmän: Zarandi, Marta, Varga, Jozsef L., Schally, Andrew V., Horvath, Judit E., Toller, Gabor L., Kovacs, Magdolna, Letsch, Markus, Groot, Kate, Armatis, Patricia, Halmos, Gabor
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2006
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450219/
https://ncbi.nlm.nih.gov/pubmed/16537407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511348103
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