Origin-specific unwinding of herpes simplex virus 1 DNA by the viral UL9 and ICP8 proteins: Visualization of a specific preunwinding complex

Eitemau Tebyg

• The herpes simplex virus type 1 origin-binding protein carries out origin specific DNA unwinding and forms stem-loop structures.
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• Unwinding of the box I element of a herpes simplex virus type 1 origin by a complex of the viral origin binding protein, single-strand DNA binding protein, and single-stranded DNA
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• Herpes simplex virus origin-binding protein (UL9) loops and distorts the viral replication origin.
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• Unwinding of a Herpes Simplex Virus Type 1 Origin of Replication (Ori(S)) by a Complex of the Viral Origin Binding Protein and the Single-Stranded DNA Binding Protein
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• An initial ATP-independent step in the unwinding of a herpes simplex virus type I origin of replication by a complex of the viral origin-binding protein and single-strand DNA-binding protein
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  Cyhoeddwyd: (2001)