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Unwinding of the box I element of a herpes simplex virus type 1 origin by a complex of the viral origin binding protein, single-strand DNA binding protein, and single-stranded DNA

The herpes simplex virus type 1 (HSV-1) genome contains three origins of replication: ori(L) and two copies of ori(S). These origins contain specific sequences, box I and box II, linked by an AT-rich segment, that are recognized by an HSV-1-encoded origin binding protein (UL9 protein) which also pos...

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Bibliografiske detaljer
Main Authors: Lee, Sam S.-K., Lehman, I. R.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences of the USA 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC20283/
https://ncbi.nlm.nih.gov/pubmed/9096307
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