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Origin-specific unwinding of herpes simplex virus 1 DNA by the viral UL9 and ICP8 proteins: Visualization of a specific preunwinding complex

Herpes simplex virus 1 contains three origins of replication; two copies of oriS and one of a similar sequence, oriL. Here, the combined action of multiple factors known or thought to influence the opening of oriS are examined. These include the viral origin-binding protein, UL9, and single-strand b...

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Detalhes bibliográficos
Main Authors: Makhov, Alexander M., Lee, Sam S.-K., Lehman, I. Robert, Griffith, Jack D.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC298698/
https://ncbi.nlm.nih.gov/pubmed/12552114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0237171100
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