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Unwinding of a Herpes Simplex Virus Type 1 Origin of Replication (Ori(S)) by a Complex of the Viral Origin Binding Protein and the Single-Stranded DNA Binding Protein

A herpes simplex virus type 1 (HSV-1) Ori(S) analogue in which the A+T sequence linking the box I and II elements was replaced by two single-stranded oligo(dT)s is unwound by the UL9 protein-ICP8 complex. Unwinding of wild-type Ori(S) by the UL9 protein-ICP8 complex was also observed under condition...

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Bibliografiske detaljer
Main Authors: He, Xiaodun, Lehman, I. R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC112062/
https://ncbi.nlm.nih.gov/pubmed/10823882
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