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CD4 and CD8 molecules can physically associate with the same T-cell receptor.
The expression of the cell-surface glycoproteins CD4 and CD8 on functionally mature T cells is usually mutually exclusive and correlates with class II and class I major histocompatibility complex (MHC) restriction, respectively. CD4 and CD8 function by binding to class II and class I MHC molecules o...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1989
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298640/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2513572/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.24.10044 |
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