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Coaggregation of the T-cell receptor with CD4 and other T-cell surface molecules enhances T-cell activation.

The CD4 molecule, expressed by T cells restricted by class II major histocompatibility complex (MHC) molecules, is believed to play a role in T-cell activation. We have previously suggested that CD4 interacts with the T-cell receptor for antigen (TCR) and with class II MHC and that this dual interac...

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Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Owens, T, Fazekas de St Groth, B, Miller, J F
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1987
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299722/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3501123/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.24.9209
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