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CD4 and CD8 molecules can physically associate with the same T-cell receptor.

The expression of the cell-surface glycoproteins CD4 and CD8 on functionally mature T cells is usually mutually exclusive and correlates with class II and class I major histocompatibility complex (MHC) restriction, respectively. CD4 and CD8 function by binding to class II and class I MHC molecules o...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Gallagher, P F, Fazekas de St Groth, B, Miller, J F
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1989
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298640/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2513572/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.24.10044
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