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Alteration of substrate specificity for the endoribonucleolytic cleavage of RNA by the Tetrahymena ribozyme.

A shortened form of the intervening sequence of the self-splicing RNA from Tetrahymena thermophila catalyzes sequence-specific cleavage of RNA. Cleavage site selection involves a base-pairing interaction between the substrate RNA and a binding site within the intervening sequence. Single-base change...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Murphy, F L, Cech, T R
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298465/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2480597/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.23.9218
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