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Characterization of human adenovirus 35 and derivation of complex vectors

BACKGROUND: Replication-deficient recombinant adenoviral vectors based on human serotype 35 (Ad35) are desirable due to the relatively low prevalence of neutralizing antibodies in the human population. The structure of the viral genome and life cycle of Ad35 differs from the better characterized Ad5...

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Autors principals: McVey, Duncan, Zuber, Mohammed, EttyReddy, Damodar, Reiter, Christopher D, Brough, Douglas E, Nabel, Gary J, King, C Richter, Gall, Jason G D
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984591/
https://ncbi.nlm.nih.gov/pubmed/20959004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-7-276
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