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Characterization of human adenovirus 35 and derivation of complex vectors

BACKGROUND: Replication-deficient recombinant adenoviral vectors based on human serotype 35 (Ad35) are desirable due to the relatively low prevalence of neutralizing antibodies in the human population. The structure of the viral genome and life cycle of Ad35 differs from the better characterized Ad5...

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Main Authors: McVey, Duncan, Zuber, Mohammed, EttyReddy, Damodar, Reiter, Christopher D, Brough, Douglas E, Nabel, Gary J, King, C Richter, Gall, Jason G D
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984591/
https://ncbi.nlm.nih.gov/pubmed/20959004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-7-276
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