Characterization of human adenovirus 35 and derivation of complex vectors

BACKGROUND: Replication-deficient recombinant adenoviral vectors based on human serotype 35 (Ad35) are desirable due to the relatively low prevalence of neutralizing antibodies in the human population. The structure of the viral genome and life cycle of Ad35 differs from the better characterized Ad5...

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Main Authors: McVey, Duncan, Zuber, Mohammed, EttyReddy, Damodar, Reiter, Christopher D, Brough, Douglas E, Nabel, Gary J, King, C Richter, Gall, Jason G D
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984591/
https://ncbi.nlm.nih.gov/pubmed/20959004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-7-276
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