Functional Genetic Variants in the 3′-Untranslated Region of Sulfotransferase Isoform 1A1 (SULT1A1) and Their Effect on Enzymatic Activity

Sulfotransferase isoform 1A1 (SULT1A1) is the most highly expressed hepatic sulfotransferase and is involved in the biotransformation of a wide variety of endo- and xenobiotics. A common single nucleotide polymorphism (SNP) in the coding region of SULT1A1, several proximal promoter SNPs, and copy nu...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Yu, Xinfeng, Dhakal, Ishwori B., Beggs, Marjorie, Edavana, Vineetha Koroth, Williams, Suzanne, Zhang, Xuemei, Mercer, Kelly, Ning, Baitang, Lang, Nicholas P., Kadlubar, Fred F., Kadlubar, Susan
التنسيق: Artigo
اللغة:Inglês
منشور في: Oxford University Press 2010
الموضوعات:
Biotransformation and Toxicokinetics
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984532/
https://ncbi.nlm.nih.gov/pubmed/20881232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq296
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