Functional Genetic Variants in the 3′-Untranslated Region of Sulfotransferase Isoform 1A1 (SULT1A1) and Their Effect on Enzymatic Activity

Sulfotransferase isoform 1A1 (SULT1A1) is the most highly expressed hepatic sulfotransferase and is involved in the biotransformation of a wide variety of endo- and xenobiotics. A common single nucleotide polymorphism (SNP) in the coding region of SULT1A1, several proximal promoter SNPs, and copy nu...

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Main Authors: Yu, Xinfeng, Dhakal, Ishwori B., Beggs, Marjorie, Edavana, Vineetha Koroth, Williams, Suzanne, Zhang, Xuemei, Mercer, Kelly, Ning, Baitang, Lang, Nicholas P., Kadlubar, Fred F., Kadlubar, Susan
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2010
Assuntos:
Biotransformation and Toxicokinetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984532/
https://ncbi.nlm.nih.gov/pubmed/20881232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq296
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