Functional Genetic Variants in the 3′-Untranslated Region of Sulfotransferase Isoform 1A1 (SULT1A1) and Their Effect on Enzymatic Activity

Sulfotransferase isoform 1A1 (SULT1A1) is the most highly expressed hepatic sulfotransferase and is involved in the biotransformation of a wide variety of endo- and xenobiotics. A common single nucleotide polymorphism (SNP) in the coding region of SULT1A1, several proximal promoter SNPs, and copy nu...

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Bibliografiset tiedot
Päätekijät: Yu, Xinfeng, Dhakal, Ishwori B., Beggs, Marjorie, Edavana, Vineetha Koroth, Williams, Suzanne, Zhang, Xuemei, Mercer, Kelly, Ning, Baitang, Lang, Nicholas P., Kadlubar, Fred F., Kadlubar, Susan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2010
Aiheet:
Biotransformation and Toxicokinetics
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984532/
https://ncbi.nlm.nih.gov/pubmed/20881232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq296
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