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Sulfation of fulvestrant by human liver cytosols and recombinant SULT1A1 and SULT1E1
Fulvestrant (Faslodex™) is a pure antiestrogen that is approved to treat hormone receptor-positive metastatic breast cancer in postmenopausal women. Previous studies have demonstrated that fulvestrant metabolism in humans involves cytochromes P450 and UDP-glucuronosyltransferases (UGTs). To date, fu...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Dove Medical Press
2011
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3400326/ https://ncbi.nlm.nih.gov/pubmed/22822301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S25418 |
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