Inhibition of Ca2+/calmodulin-dependent protein kinase II by arachidonic acid and its metabolites.
A variety of evidence indicates that activation of Ca2+/calmodulin-dependent protein kinase II (CaM-kinase II) in nerve terminals leads to enhanced neurotransmitter release. Arachidonic acid and its 12-lipoxygenase metabolite, 12-hydroperoxyeicosatetraenoic acid (12-HPETE), have been suggested to ac...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1989
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298320/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2554319/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.21.8550 |
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