The class IA phosphatidylinositol 3-kinase p110-β subunit is a positive regulator of autophagy

Autophagy is an evolutionarily conserved cell renewal process that depends on phosphatidylinositol 3-phosphate (PtdIns(3)P). In metazoans, autophagy is inhibited by PtdIns(3,4,5)P(3), the product of class IA PI3Ks, which mediates the activation of the Akt–TOR kinase cascade. However, the precise fun...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Dou, Zhixun, Chattopadhyay, Mohar, Pan, Ji-An, Guerriero, Jennifer L., Jiang, Ya-Ping, Ballou, Lisa M., Yue, Zhenyu, Lin, Richard Z., Zong, Wei-Xing
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2010
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2983054/
https://ncbi.nlm.nih.gov/pubmed/21059846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201006056
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