Alterations in mGluR5 Expression and Signaling in Lewy Body Disease and in Transgenic Models of Alpha-Synucleinopathy – Implications for Excitotoxicity

Dementia with Lewy bodies (DLB) and Parkinson's Disease (PD) are neurodegenerative disorders of the aging population characterized by the abnormal accumulation of alpha-synuclein (alpha-syn). Previous studies have suggested that excitotoxicity may contribute to neurodegeneration in these disord...

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Detalhes bibliográficos
Main Authors: Price, Diana L., Rockenstein, Edward, Ubhi, Kiren, Phung, Van, MacLean-Lewis, Natalie, Askay, David, Cartier, Anna, Spencer, Brian, Patrick, Christina, Desplats, Paula, Ellisman, Mark H., Masliah, Eliezer
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982819/
https://ncbi.nlm.nih.gov/pubmed/21103359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014020
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