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Lack of Original Antigenic Sin in Recall CD8(+) T Cell Responses

In the real world, mice and men are not immunologically naive, having been exposed to numerous antigenic challenges. Prior infections sometimes negatively impact the response to a subsequent infection. This can occur in serial infections with pathogens sharing cross-reactive Ags. At the T cell level...

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Autori principali: Zehn, Dietmar, Turner, Michael J., Lefrançois, Leo, Bevan, Michael J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982183/
https://ncbi.nlm.nih.gov/pubmed/20439913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000149
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