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Lack of Original Antigenic Sin in Recall CD8(+) T Cell Responses
In the real world, mice and men are not immunologically naive, having been exposed to numerous antigenic challenges. Prior infections sometimes negatively impact the response to a subsequent infection. This can occur in serial infections with pathogens sharing cross-reactive Ags. At the T cell level...
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Main Authors: | , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
2010
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2982183/ https://ncbi.nlm.nih.gov/pubmed/20439913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000149 |
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