Construction of a recombinant human parvovirus B19: adeno-associated virus 2 (AAV) DNA inverted terminal repeats are functional in an AAV-B19 hybrid virus.
To facilitate genetic analysis of the human pathogenic parvovirus B19, we constructed a hybrid B19 viral genome in which the defective B19 inverted terminal repeats were replaced with the full-length inverted terminal repeats from a nonpathogenic human parvovirus, the adeno-associated virus 2 (AAV)....
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1989
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298218/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2554300/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.20.8078 |
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