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Construction of a recombinant human parvovirus B19: adeno-associated virus 2 (AAV) DNA inverted terminal repeats are functional in an AAV-B19 hybrid virus.

To facilitate genetic analysis of the human pathogenic parvovirus B19, we constructed a hybrid B19 viral genome in which the defective B19 inverted terminal repeats were replaced with the full-length inverted terminal repeats from a nonpathogenic human parvovirus, the adeno-associated virus 2 (AAV)....

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Srivastava, C H, Samulski, R J, Lu, L, Larsen, S H, Srivastava, A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298218/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2554300/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.20.8078
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