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An N-Terminal Polybasic Motif of Gα(q) Is Required for Signaling and Influences Membrane Nanodomain Distribution
Regions of basic amino acids in proteins can promote membrane localization through electrostatic interactions with negatively charged membrane lipid head groups. Previous work showed that the heterotrimeric G protein subunit α(q) contains a polybasic region in its N terminus that contributes to plas...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Pharmacology and Experimental Therapeutics
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2981394/ https://ncbi.nlm.nih.gov/pubmed/20664004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.066340 |
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