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N-terminal polybasic motifs are required for plasma membrane localization of Gαs AND Gαq

Heterotrimeric G proteins typically localize at the cytoplasmic face of the plasma membrane where they interact with heptahelical receptors. For G protein α subunits, multiple membrane targeting signals, including myristoylation, palmitoylation, and interaction with βγ subunits, facilitate membrane...

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Bibliographic Details
Main Authors: Crouthamel, Marykate, Thiyagarajan, Manimekalai M., Evanko, Daniel S., Wedegaertner, Philip B.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2603300/
https://ncbi.nlm.nih.gov/pubmed/18647648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2008.06.019
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