Improved Detection of Mutated Human Cytomegalovirus UL97 by Pyrosequencing

Ganciclovir (GCV) resistance frequently occurs upon prolonged treatment of ongoing active human cytomegalovirus (HCMV) infection in individuals with immature or compromised immune functions (e.g., recipients of solid-organ and hematopoietic stem cell transplants). Using pyrosequencing (PSQ), we esta...

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Autores principales: Schindele, Birgit, Apelt, Luise, Hofmann, Jörg, Nitsche, Andreas, Michel, Detlef, Voigt, Sebastian, Mertens, Thomas, Ehlers, Bernhard
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Materias:
Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981242/
https://ncbi.nlm.nih.gov/pubmed/20876379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00802-10
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