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Structural Consequences of β-Amino Acid Preorganization in a Self-Assembling α/β-Peptide: Fundamental Studies of Foldameric Helix Bundles

We report high-resolution crystal structures of six new α/β-peptide foldamers that have a regular α-residue/α-residue/β-residue (ααβ) backbone repeat pattern. All of these foldamers were crystallized from aqueous solution, and all display four-helix bundle quaternary structure in the crystalline sta...

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Detalhes bibliográficos
Main Authors: Price, Joshua L., Horne, W. Seth, Gellman, Samuel H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981134/
https://ncbi.nlm.nih.gov/pubmed/20718422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja103543s
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