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Interplay among side chain sequence, backbone composition, and residue rigidification in polypeptide folding and assembly

The extent to which polypeptide conformation depends on side-chain composition and sequence has been widely studied, but less is known about the importance of maintaining an α-amino acid backbone. Here, we examine a series of peptides with backbones that feature different repeating patterns of α- an...

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Detalles Bibliográficos
Main Authors: Horne, W. Seth, Price, Joshua L., Gellman, Samuel H.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453709/
https://ncbi.nlm.nih.gov/pubmed/18587049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801135105
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